The usefulness of the Hotchkiss-McManus stain for the diagnosis of the deep mycoses.

The isolation of pathogenic fungi is more difficult than most physicians appreciate and the average hospital bacteriology laboratory approaches the problem in a half-hearted and uninstructed manner. Too often the diagnosis is a “coup de grace” administered by the pathologist at the clinical pathological conference. As a matter of fact, a considerable number of deep mycoses must go unrecognized each year despite the provision of adequate material to the pathologist for at least a tentative diagnosis. There are a number of reasons for this state of affairs; the two which are outstanding implicate both the clinician and the pathologist.